Vitiligo

Vitiligo is an autoimmune skin disorder in which the body’s immune system mistakenly attacks the healthy cells, especially melanocytes, which are pigment-producing cells in the skin responsible for the colour of the skin and protection from UV radiation. In vitiligo, the destruction of melanocytes results in white, depigmented patches on various parts of the body. It affects people of all ages and genders. Early detection and treatment are beneficial for healing vitiligo and stopping its further spread. 

Types of Vitiligo 

Non-segmental vitiligo: This is the most common form of vitiligo, characterised by similar white patches on both sides of the body. It has the following subtypes. 

  • Generalised: Patches are  present on any part of the body
  • Acrofacial: In this type, patches are present on the face, hands, and feet. 
  • Mucosal: The patches are present on the mouth and genital parts
  • Universal: In this type, the paths are present in the overall body 
  • Other types include Mixed and Focal: In this type, one or more isolated patches are present.

These are the subtypes of non-segmental vitiligo. 

Segmental vitiligo: It affects only one side of the body and usually does not cross the midline of the body. The subtypes of segmental vitiligo are as follows: 

  • Focal: In this type, one or isolated patches are present. 
  • Thrichrome: The patches are present in three different shades, such as usual, depigmented, hypopigmented, or less pigmented. 
  • Quadrichrome: In this type, there is the presence of dark brown dots during repigmentation
  • Confetti: This type presents confetti-like spots on the body. 

Causes and Risk Factors of Vitiligo

  • Autoimmune destruction of monocytes due to abnormal immune response. 
  • Vitiligo often runs in families, so a person with a family history of the condition may be at a higher risk of developing it. 
  • Autoimmune diseases like thyroid disorder, type 1 diabetes, and lupus can cause vitiligo. 
  • Triggers such as sunburn, emotional stress, and chemical exposure can exacerbate the symptoms of vitiligo. 

Symptoms of Vitiligo 

  • Milky white patches of skin are progressive. 
  • The hair in the affected area may turn white, also known as leukotrichia
  • Loss of pigmentation on the mucus membranes 
  • Itching before depigmentation
  • Psychological impacts like low self-esteem, anxiety and social distress. 

Diagnosis of Vitiligo 

  • It is based on clinical examination and patient history 
  • Wood’s lamp test to observe the depigmented areas under the UV light. 
  • Skin biopsy is done
  • Blood tests to rule out autoimmune conditions like thyroid disorder, lupus, etc., Ophthalmologic evaluation if eye symptoms are present

Treatment of Vitiligo  

  • Ointment 
  • Oral medications
  • Intravenous medications

Diet and Lifestyle for Vitiligo Management and Protection are essential; hence, wear proper clothing. 

  • Use gentle and mild soaps.
  • Psychological support and counselling help to improve self-esteem and social anxieties, which may develop due to vitiligo. 
  • Adopt a healthy lifestyle. Eat a balanced diet and engage in regular exercise. 

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